Prutton was ineligible for Saturday's defeat at Leeds as he was on loan from the Elland Road club.
Prutton, who has since signed a permanent deal with the Us, could start his first game after grabbing a goal on his debut as a substitute against MK Dons.
Boss Aidy Boothroyd looks set to be without defensive duo Christian Ribeiro and Paul Reid once again.
Both players are struggling with groin injuries so John White and Matt Heath are likely to keep their places.
Winger Ashley Vincent (ankle) and defender Ashley Beevers (shoulder) are back in training following their long lay-offs but will not be involved yet.
Source: Team Talk


