Victory would have moved the Us to within three points of the Yorkshire club, but the stalemate leaves them five points adrift of the automatic promotion places.
The 26-year-old has made 35 appearances for the U's since joining from Carlisle last year, but has not featured since the 7-0 FA Cup defeat by Preston in January.
Reid has been out for a month with a calf injury but is close to returning while fellow centre-half and skipper Magnus Okuonghae is pushing for a start after being left on the bench for last weekend's defeat by Bristol Rovers.
This week FootyMad's match preview focuses on the game between Colchester United and Brighton & Hove Albion at 19:45 on Monday, 8th March 2010 in the League One.
The long-serving 29-year-old feels the U's, who currently lie fourth in League One, are capable of securing a return to the Championship under boss Aidy Boothroyd.